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Another new CCR5 inhibitor – SCH532706 Another CCR5 inhibitor being investigated in clinical trials in SCH532706. The potency of this drug is boosted by ritonavir.

The drug is in the early phases of development, but results from twelve HIV-positive patients (four of whom were taking anti-HIV treatment for the first time) show that ten days of treatment with SCH532706/ritonavir significantly lowered viral load and increased CD4 cell count.

The most common side-effect was an upset stomach, but one person did develop inflammation of the sac around the heart (pericarditis), which the researchers think was “possibly related” to the drug.

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